Selumetinib (Koselugo,Semedx)

Selumetinib inhibits the activity of MEK1/2 proteins, blocks the RAS/RAF/MEK/ERK signaling pathway, and thereby suppresses the proliferation and survival of tumor cells.

10mg*60capsules
25mg*60capsules

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Selumetinib Medication Q&A

What other drugs will affect selumetinib

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplement···【More】
Update: 11 Mar,2026Source: BigbearViews: 127
What Are the Adverse Reactions of Selumetinib

Severe Adverse ReactionsInclude abnormal diarrhea, anemia (manifesting as fatigue, dizziness, etc.), and persistent fever.Common Adverse ReactionsVomi···【More】
Update: 11 Mar,2026Source: BigbearViews: 111
What to Do If Selumetinib Is Overdosed

There is currently no specific antidote for selumetinib overdose. In the event of an overdose, immediately monitor the patient for signs of adverse re···【More】
Update: 11 Mar,2026Source: BigbearViews: 105
What to Do If a Dose of Selumetinib Is Missed

If a dose is missed, it can only be made up if more than 6 hours remain before the next scheduled dose. If less than 6 hours remain until the next dos···【More】
Update: 11 Mar,2026Source: BigbearViews: 110